Surgery presentations (MU)
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Items in this collection are public presentations made by Department of Surgery faculty, staff, and students, either alone or as co-authors, and which may or may not have been published in an alternate format. Items may contain more than one file type.
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Item Research in motion(2010-03) Bal, B. Sonny; University of Missouri (System); Missouri Life Sciences Summit (2010: University of Missouri--Kansas City)Orthopaedic disorders of the major joints, specifically, osteoarthritis of the hip and knee joints have an enormous economic and functional impact on our society, affecting millions of patients every day. In the late 1960s and early 1970s, replacement of diseased joints with metal and plastic components was developed as a salvage technique for elderly, and relatively sedentary patients. Now, with an aging and active population that expects to maintain function and mobility, the demand for major joint reconstruction is increasing worldwide. Younger, heavier, and active patients place greater demands on biomaterials and implants. Our collaborative team is focused on developing new biomaterials that can meet the challenge of skeletal repair, and joint replacement, and on exploring tissue-engineered cartilage as a possible biological replacement of diseased and arthritic joints. An interdisciplinary team approach to these goals has resulted in peer-reviewed publications, graduate student education opportunities, and extramural funding. Going forward, a major goal is to leverage our resources to create products that can be positioned profitably in the commercially-attractive orthopaedic device market.Item Do patients with craniosynostosis have increased incidence of auditory neuropathy newborns? [abstract](2010-02) Scheele, Jessica; University of Missouri--Columbia. School of Medicine; Health Sciences Research Day (2010 : University of Missouri)Objective: To investigate the incidence of abnormal auditory brainstem response (ABR) with normal otoacoustic emissions, in newborn patients with craniosynostosis as compared to published standards. Design: A retrospective review of consecutive patients with single or multiple-suture craniosynostosis seen between 2002 and 2009 was performed. Patients identified by the diagnostic code of craniosynostosis were divided into groups based on the involved suture(s). The newborn ABR screening and, if patients were referred, diagnosis from audiologic diagnostic testing were obtained from the Missouri Department of Health. Institutional review board approval was obtained. Patients: One hundred and thirty-five patients were identified. Seventy-two were excluded; 3 were listed as "missed" and 69 were not born in-state. The 63 patients included in the study were grouped by involved sutures: 2 left coronal, 7 right coronal, 2 nonsyndromic bicoronal, 3 syndromic bicoronal, 13 sagittal, 17 operative metopic, 15 nonoperative metopic, 1 pansynostosis, and 3 multiple-suture. Main Outcome Measures: The newborn screening results for each patient were recorded as well as the diagnosis from audiologic diagnostics if the patient was referred. Results: Of the 63 patients, 94% (59/63) passed their ABR screening. Four were referred for diagnostic exam in both ears. Of those, one had a normal exam (right coronal) and three did not have diagnostic exams on file (right coronal, bicoronal syndromic and bicoronal non-syndromic). Conclusions: According to the Centers for Disease Control, 1.8 percent of newborns failed their ABR screening in 2007. Of those, 37% were found to have normal hearing on diagnostic exam. Although our study was inconclusive due to inadequate state records, it does demonstrate an increased incidence of abnormal ABR's in patients with coronal craniosynostosis. This is consistent with a recent publication that demonstrated a higher incidence of abnormal ABR's in syndromic coronal craniosynostosis. If auditory abnormalities are present at birth, as our study suggests, the etiology would likely be unrelated to increased intracranial pressures.Item Do Patients with Craniosynostosis Have an Increased Incidence of Auditory Neuropathy as Newborns?(2010-02) Scheele, Jessica; Hubbard, Bradley A.; Rice, Gale B.; Muzaffar, Arshad R.; University of Missouri (System); Missouri Life Sciences Summit (2010: University of Missouri--Kansas City)OBJECTIVE: To investigate the incidence of auditory neuropathy, abnormal auditory brainstem response (ABR) with normal otoacoustic emissions, in newborn patients with craniosynostosis as compared to published standards. DESIGN: A retrospective review of consecutive patients with single or multiple-suture craniosynostosis who were seen between 2002 and 2009. Patients identified by the diagnostic code of craniosynostosis were divided into groups based on suture involvement. The newborn ABR screening and, if patients were referred, diagnosis from audiologic diagnostic testing were obtained from the Missouri Department of Health. Institutional review board approval was obtained. PATIENTS: One hundred and thirty-five patients were identified. Seventy-two were excluded; 3 were listed as “missed” and 69 were not born in-state. The 63 patients included in the study were grouped by involved sutures: 2 left coronal, 7 right coronal, 2 nonsyndromic bicoronal, 3 syndromic bicoronal, 13 sagittal, 17 operative metopic, 15 nonoperative metopic, 1 pansynostosis, and 3 multiple-suture. MAIN OUTCOME MEASURES: The newborn screening results for each patient were recorded as well as the diagnosis from audiologic diagnostics if the patient was referred. RESULTS: Of the 63 patients, 94% (59/63) passed their ABR screening. Four were referred for diagnostic exam in both ears. Of those, one had a normal exam (right coronal) and three did not have diagnostic exams on file (right coronal, bicoronal syndromic and bicoronal non-syndromic). CONCLUSIONS: According to the Centers for Disease Control, 1.8 percent of newborns failed their ABR screening in 2007. Of those, 37% were found to have normal hearing on diagnostic exam. Although our study was inconclusive due to inadequate state records, it does demonstrate an increased incidence in abnormal ABR's in patients with coronal craniosynostosis. This is consistent with a recent publication that demonstrated higher incidence of abnormal ABR's in syndromic coronal craniosynostosis. If auditory abnormalities are present at birth, as our study suggests, the etiology would be unrelated to increased intracranial pressures.Item MU Biodesign and Innovation Program(2010-02) Dale, Paul S.; Jahnsen, M.; Hays, W.; Rone, Rebecca; University of Missouri (System); Missouri Life Sciences Summit (2010: University of Missouri--Kansas City)The MU Biodesign and Innovation Program (MUBIP) centers its efforts off two tiers: (1) formal educational training through a biodesign and innovation fellowship and (2) interdisciplinary faculty collaboration. The Department of Surgery and College of Engineering on the University of Missouri campus in Columbia recognizes the growing need to improve patient care and desire to impact this arena through the collaborative development of MUBIP. MUBIP goals are to successfully bring new medical technologies and health care solutions into the market while producing high quality innovative professionals with the desire and knowledge to continue producing new medical technologies within our program, the University of Missouri, MU Biodesign affiliates, corporations or through the establishment of new companies resulting in economic gains. Formal Educational Training: The education tier is focused primarily on the fellowship. The experience simulates, in a compressed one-year timeframe, the phases of a start-up medical device company. The fellowship consists of a three member team including a surgeon, engineering with at least a masters degree, and business professional with a MBA. The fellowship team start date is July 1 and ends June 30. The fellowship year structure is divided into three phases that provide observation and hands-on experience in clinical, engineering and business environments. Phase 1 is clinical immersion; Phase 2 engineering design and development, finishing with Phase 3, business practices. Each phase is approximately 4 months with overlap throughout the year. In addition to observation and hands on training in each phase the fellows attend lectures related to the biodesign process, surgery, engineering and business. Lectures are presented by faculty from the Department of Surgery, College of Engineering, entrepreneurs, angel fund investors, venture capitalists, industry leaders, founders from start up companies, and other successful biodesign related individuals from the community and nationwide. Faculty, staff, residents and students are welcome to attend these lectures. Interdisciplinary Faculty Collaborations: Interdisciplinary faculty collaboration is the other tier of MUBIP. MUBIP goal is to facilitate collaboration between faculty within the University of Missouri Campus through interdisciplinary research and education. With the MUBIP mission focused to improve health care through invention and implementation of new medical technologies, we believe this can be accomplish through MUBIP guidance and support from the faculty members collaborating to build on existing relationships and form new relationships to invent innovative medical technologies. Conclusion: MU Biodesign & Innovation Program is a new innovative way to grow, build and promote new medical technologies to improve patient care. The education is a novel way to help surgeons, engineers and business people learn the process from napkin to market and prepare them for a future in medical device development. This program has the ability to impact future patient care with a generation of knowledgeable successful inventors. Collaboration is a key factor to continue improving patient care. Technologies, research and knowledge continue to grow; however, to maximize the potential of new inventions and improve patient care, it is crucial to bring engineers and surgeons together to be leaders in today's changing world.Item Training Tomorrows Entrepreneurs Today(2010-02) Dale, Paul S.; Jahnsen, M.; McGowan, D.; Scheller, G.; University of Missouri (System); Missouri Life Sciences Summit (2010: University of Missouri--Kansas City)The MU Biodesign and Innovation Program (MUBIP) is focused on improving health care through invention and implementation of new medical technologies. The focus of the program is formal educational training of three fellows with a focus on biodesign and innovation. Additionally, the program is dedicated to the development and facilitation of interdisciplinary collaboration between faculty and students to increase innovation at the University of Missouri. With the financial support of the Department of Surgery, the School of Engineering and the Missouri Technology Corporation (MTC) the MUBIP is in its 3rd successful year. The program brings the brightest young minds with an M.D. degree, an engineer with a masters or PhD, and a business professional with an MBA together as a design team. The fellowship year structure is divided into three phases. Phase 1 is clinical immersion; Phase 2 engineering design and development, finishing with Phase 3, business practices. Each phase is approximately 4 months with overlap throughout the year. In addition to observation and hands on training in each phase the fellows attend lectures related to the biodesign process. Lectures are presented by faculty and staff from the Department of Surgery, College of Engineering, entrepreneurs, angel fund investors, venture capitalists, industry leaders, founders from startup companies, and other successful biodesign related individuals from the community and nationwide.