The use of radioisotopes (Synovetin OA®) for the treatment of equine osteoarthritis
No Thumbnail Available
Authors
Meeting name
Sponsors
Date
Journal Title
Format
Thesis
Subject
Abstract
Osteoarthritis (OA) is commonly diagnosed in equine patients as a cause of lameness. There are a variety of medical and surgical treatment methods to manage OA in horses, though many treatment options are chondrotoxic or are considered salvage procedures. Radiosynoviocentesis, the intra-articular injection of a radioisotope, is used in humans and dogs for the medical management of OA. Tin 117m radio-colloid (Synovetin OA®) has been used successfully in dogs to treat grade 1 and 2 elbow OA. The aims of this study were to determine: (1) any adverse effects, including increased lameness, following intraarticular injection with Synovetin OA® and (2) if there is evidence of clinical progression of OA following intraarticular injections with respect to radiographs and/or synovial fluid analysis. Four horses with naturally occurring lameness due to OA were injected with Synovetin OA® intra-articularly. The horses were then monitored over a six-month period using an inertial-sensor system to measure the degree of lameness. Synovial fluid analysis and radiography were also used to characterize posttreatment progress. Although one horse developed self-limiting cellulitis, no other adverse effects were observed. Lameness had not significantly changed at the conclusion of the study compared to initial assessment. There were no significant radiographic changes following radiosynoviocentesis. These results suggest that Synovetin OA® appears to be a safe treatment option for OA in horses and further research is needed to determine the most appropriate treatment approach.
Table of Contents
PubMed ID
Degree
M.S.