Is bicarbonate therapy effective in preventing CKD progression?
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Q: Is bicarbonate therapy effective in preventing CKD progression? Evidence-based answer: YES. Long-term sodium bicarbonate therapy slightly slows the loss of renal function in patients with chronic kidney disease (CKD) and may moderately reduce progression to end-stage renal disease (strength of recommendation [SOR]: B, meta-analyses of lower-quality randomized controlled trails [RCTs]). Therapy duration of 1 year or less may not be beneficial (SOR: C, secondary analyses in meta-analyses).
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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.