Brain phenotypes in a mouse model for Apert Syndrome [abstract]
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Abstract
Apert Syndrome (AS) is one of several fibroblast growth factor receptor (FGFR) related craniosynostosis syndromes. Individuals with AS display craniofacial dysmorphology and a constellation of central nervous system anomalies. In this study we present quantitative comparisons of brain phenotypes in a mouse model for Apert syndrome, the Fgfr2+/S252W mouse.
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