Cutaneous squamous cell carcinoma metastasis to parotid, analysis of outcomes with positive margins at initial resection
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"Several studies have been conducted evaluating prognostic factors in primary salivary gland cancer as well as in cutaneous squamous cell carcinoma (SCCa) with metastasis to the salivary glands. However, there is currently a gap in the literature regarding the outcomes specifically related to positive margins at initial marginal analysis for cutaneous SCCa in patients with metastasis to the parotid. Patients with metastasis of cutaneous squamous cell carcinoma (SCCa) to intraparotid lymph nodes are often treated with parotidectomy (Figures 2 and 3) and neck dissection (Figure 1). Pathology reports may comment on the presence of carcinoma at the inked edge of a specimen, but the clinical significance of this 'positive margin' is understudied. With this study, we aim to expand on the current literature to specifically evaluate overall survival and disease-free survival rates in patients who underwent surgery with parotidectomy and neck dissection for metastatic SCCa to the parotid gland."--Introduction.
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