Rare case of clear cell sarcoma in a young female

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Clear Cell Sarcoma of Tendon and Aponeuroses (CCTA), also known as Melanoma of soft tissue is a rare and highly malignant soft tissue neoplasm which mostly occurs in young adults A 26-year-old female presented with pain and thickened soft tissue in the popliteal fossa at the posterior aspect of the left knee. Ultrasonography demonstrated a cystic mass with irregular wall and internal debris representing a complex popliteal cyst. Further work-up with MRI demonstrated a cystic mass lateral to the semimembranosus muscle tendon. Excisional biopsy of the mass was consistent with malignant neoplasm with plasmacytoid features. Immunoperoxidase and cytogenic studies supported the diagnosis for Clear Cell Sarcoma arising from the tendon sheath.

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