Aspirin in Patients with Acute Ischemic Stroke

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Authors

Park, Michael K.
 Smith, Peter C.
 Wanserski, Gerri R.

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Date

2009

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Article

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atherothrombotic disease, International Stroke Trial (IST), Chinese Acute Stroke Trial (CAST), hemorrhagic stroke

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Abstract

Aspirin in a daily dose of 160 to 300 mg initiated within 48 hours of symptom onset results in a net decrease in morbidity and mortality caused by acute ischemic stroke (Strength of Recommendation [SOR]: A, based on a systematic review), regardless of the availability of computed tomography (CT). (SOR: A, based on a meta-analysis). Aspirin is as effective as anticoagulants in this regard and causes less harm (SOR: A, based on a systematic review), but it should not be used in patients receiving thrombolytic therapy. (SOR: B, based on one randomized controlled trial [RCT]).

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http://hdl.handle.net/10355/3985

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OpenAccess.

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.

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Clinical Inquiries, 2009