Does high dietary soy intake affect a woman's risk of primary or recurrent breast cancer?
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Q. Does high dietary soy intake affect a woman's risk of primary or recurrent breast cancer? Evidence-based answer: No, it doesn't affect the risk of primary breast cancer, but it does (favorably) affect the risk of cancer recurrence. Compared with diets low in soy, high dietary intake of soy protein or soy isoflavones isn't associated with any alteration in the risk of developing primary breast cancer (strength of recommendation [SOR]: B, systematic review of prospective cohort studies). In patients with breast cancer, however, consuming a diet high in soy is associated with a 25% decrease in cancer recurrence and a 15% decrease in mortality (SOR: B, prospective cohort studies).
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