Brain Natriuretic Peptide Levels for Ruling Out Heart Failure

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A BNP level less than 100 pg per mL (100 ng per L) can rule out heart failure. (Strength of Recommendation [SOR]: A, based on meta-analyses.) BNP levels should be used when the pretest probability of heart failure based on overall clinical assessment is of an intermediate likelihood. (SOR: A, based on meta-analyses.)

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