What are the best prophylactic drugs for migraine?
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Beta-blockers without intrinsic sympathomimetic activity, amitriptyline, divalproex sodium/sodium valproate, and topiramate are the most effective drugs for preventing episodic migraine (strength of recommendation: A, multiple, well-designed, randomized controlled trials [RCTs]).
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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.