Advancements in hyperpolarized xenon MRI : methodological exploration and image reconstruction for enhanced assessment of pulmonary disease

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The human respiratory system is remarkable, tirelessly facilitating the exchange of oxygen and carbon dioxide to sustain life. However, the prevalence of chronic respiratory illnesses underscores the need for advancing our understanding of lung pathophysiology and treatment. In this exploration, we emphasize the pivotal role of imaging techniques in unraveling lung structure and function, particularly through the lens of hyperpolarized xenon MRI. This investigation navigates through the complexities of respiratory health, delving into methodologies, clinical applications, and experimental procedures associated with hyperpolarized xenon MRI. We thoroughly discuss gas and dissolved phase image analysis, image reconstruction, optimization strategies, and artifact mitigation techniques to enhance the diagnostic and therapeutic capabilities of this emerging technology. Collaboration between researchers and clinicians is paramount in integrating hyperpolarized xenon MRI into respiratory medicine, ultimately improving outcomes for individuals with chronic respiratory illnesses.

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M.S.

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