How does pentoxifylline affect survival of patients with alcoholic hepatitis?
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Pentoxifylline improves short-term survival in patients admitted to the hospital with severe alcoholic hepatitis (strength of recommendation [SOR]: B, a single published randomized controlled trial [RCT]). Pentoxifylline does not improve survival when it is substituted for steroids in hospitalized patients who aren't responding to steroids (SOR: C, case series).
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