Do statins alter the risk or progression of dementia?
No Thumbnail Available
Meeting name
Sponsors
Date
Journal Title
Format
Article
Subject
Abstract
Q: Do statins alter the risk or progression of dementia? Evidence-based answer: No. Moderate-intensity statin therapy (with pravastatin or simvastatin) doesn't prevent progression to dementia in patients at increased risk. No prevention studies address high-intensity statin therapy (strength of recommendation [SOR]: A, randomized controlled trials [RCTs]). Neither moderate- nor high-intensity statin therapy (with simvastatin or atorvastatin, respectively) improves existing mild to moderately severe Alzheimer's or vascular dementia (SOR: A, RCTs). Although statin use is associated with a mild, rare, reversible delirium, it isn't linked to permanent cognitive decline (SOR: C, expert opinion).
Table of Contents
DOI
PubMed ID
Degree
Thesis Department
Rights
OpenAccess.
License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.