Sphingosine analog AAL-R enhances dendritic cell responses upon TLR7 ligation [abstract]
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Abstract
Sphingosine analogs display immune suppressive activities and thus have therapeutic potential in the treatment of autoimmune diseases. In this study, we investigated the effect of a sphingosine analog, AAL-R, on the host immunity of dendritic cell (DC) response upon the stimulation of toll-like receptors (TLRs) or a viral infection.
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