Design and characterization of biointerfaces for label-free electrochemical biosensor development for biomarker detection
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"A biosensor is an analytical device that detects a biological event and converts it into a measurable signal.1 These devices are widely used in medical diagnostics to identify biomarkers associated with different diseases. A biosensor consists of 3 primary components including an analyte, bioreceptor, and transducer.2 The analyte is the target molecule being detected, while the bioreceptor is a biomolecule that selectively binds to the analyte. The transducer is a component that converts the bio-recognition event into a detectable signal, be it optical, acoustic, or electrical in nature. Figure 1.1. illustrates the working principle of a biosensor. The intensity of the resulting signal is typically proportional to the concentration of analyte, allowing for accurate quantification. Noteworthy examples of biosensors include glucose meters for diabetes management,3 laminar flow pregnancy tests,4 and heavy metal sensors5 used in environmental monitoring." -- first page
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M.S.