Some factors on the innervation of the heart with special reference to the cardiac accelerator mechanism of the heart of the turtle Emydoidea blandingi

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The first suggestion of an accelerator nervous mechanism for the heart was given by Legallois in 1812. He found in the dog and oat that stimulation of the cord by its sudden destruction produced an increase in the force of the beat. Von Bezold[superscript 2] used a better stimulating and recording apparatus than did Legallois and again raised the question of cardiac nerves other than the vagi. He did not, however discover the pathway of the augmentory impulses from the cord to the heart. Ludwig and Thiry[superscript 3] sharply attacked the work of Von Bezold. They found that after destroying with a gal- vano-cautery all the nerves connecting the heart with the spinal cord and then stimulating the spinal cord electrically, they got the same rise in blood pressure as did Von Bezold and which he ascribed to the action of the augmentary cardiac nerves

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