Browsing by Thesis Department "Genetic area program (MU)"
Now showing items 21-26 of 26
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Molecular genetic studies of canine inherited diseases including SAMS, neuronal ceroid lipofuscinosis and dilated cardiomyopathy
(University of Missouri--Columbia, 2016)The genome of Canis lupus familiaris, the domestic dog, is an ideal tool for the study of inherited diseases. Its genome is uniquely suited for the mapping of genes that cause disease, and its reference genome has been ... -
Regulation of BK virus DNA replication by transcription factors and noncoding RNAs
(University of Missouri--Columbia, 2011)Human polyomavirus BK (BKV) asymptomatically infects 80[about]90% of people during early childhood, and establishes a life-long persistent infection without causing overt clinical symptoms. High level BKV replication occurs ... -
The role of genetic background on the phenotypic severity of the osteogensis imperfecta murine (oim) COLIA2 gene mutation throughout postnatal development
(University of Missouri--Columbia, 2006)Osteogenesis imperfecta (OI) is a diverse disease of type I collagen, the main structural protein in the body. It has been well documented that related individuals harboring the same OI-causing mutation can have very ... -
The role of mTOR in SAF-1-mediated VEGF expression and breast cancer progression
(University of Missouri--Columbia, 2015)Breast cancer is a heterogeneous disease with a huge impact on the community evident from its high indices of morbidity and mortality worldwide. In recent years, research has been extensively directed toward unravelling ... -
Studies on the mechanisms of action of the male specific lethal complex in Drosophila
(University of Missouri--Columbia, 2011)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Dosage compensation is achieved by a twofold up-regulation of the single X chromosome in male Drosophila. The inverse dosage effect produced by the ... -
Utilizing gene therapy methods to probe the genetic requirements to prevent spinal muscular atrophy /
(University of Missouri--Columbia, 2016)Spinal Muscular Atrophy is clinically recognized as a progressive weakness within the trunk and proximal limbs that will lead to breathing failure and death within infants. As a neurodegenerative genetic disease, SMA is ...