Browsing by Author/Contributor "Alexander, Stephen, 1948-"

Now showing items 1-6 of 6

  • Curcumin regulates transcription in Dictyostelium discoideum 

    Swatson III, William S. (University of Missouri--Columbia, 2016)
    Botanicals are widely used as dietary supplements and for the prevention and treatment of a myriad of diseases ranging from the common cold to depression. One in four Americans uses a botanical as part of their primary ...

  • Drug resistance in D. discoideum: isolation of 4-nitroquinoline 1-oxide resistant mutants 

    Stegner, Andrew L. (University of Missouri--Columbia, 2005)
    The drug 4-nitroquinoline 1-oxide (4NQO) displays both carcinogenic and antitumor effects, a well known characteristic of many chemotherapeutic drugs. In addition 4NQO shares a similar operating mechanism with the commonly ...

  • Making chemotherapy stronger: Targeting proteins involved in drug resistance [abstract] 

    Randall, Jean; Alexander, Hannah, 1947-; Alexander, Stephen, 1948- (University of Missouri--Columbia. Office of Undergraduate Research, 2006)
    Resistance to chemotherapy drugs is an issue faced in cancer treatment. Only some of the causes of drug resistance are known, and further study is needed in order to improve the efficacy of existing drugs and to develop ...

  • Proteomics of canine lymphoma identifies potential cancer-specific protein markers 

    McCaw, Dudley L.; Chan, Arvan S.; Stegner, Andrew L.; Mooney, Brian P.; Bryan, Jeffrey N.; Turnquist, Susan E.; Henry, Carolyn J.; Alexander, Hannah, 1947-; Alexander, Stephen, 1948- (American Association for Cancer Research, 2007)
    Purpose: Early diagnosis of cancer is crucial for the success of treatment of the disease, and there is a need for markers whose differential expression between disease and normal tissue could be used as a diagnostic tool. ...

  • Regulation of ceramide synthase 1 in cellular stress response 

    Sridevi, Priya (University of Missouri--Columbia, 2008)
    [ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Ceramides are intimately involved in a wide range of cellular processes. In mammals, de novo ceramide synthesis is catalyzed by the 6 ceramide synthase ...

  • Sphingolipid metabolic enzymes modulate anticancer drug resistance 

    Min, Junxia (University of Missouri--Columbia, 2006)
    [ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] One of the most challenging aspects of cancer therapy today is the problem of drug resistance. The aim of our research is to understand the molecular ...