Browsing by Author/Contributor "Clark, Suzanne E."

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The effect of aldosterone on fatty acid oxidation in HepG2 cells [abstract]

Pineda, Juan Camilo; Ibdah, Jamal A.; Clark, Suzanne E.; Thyfault, John P.; Szary, Nicholas M. (University of Missouri--Columbia. Office of Undergraduate Research, 2008)

The HepG2 cell line is an immorilized cell line harvested from a human hepatocellular carcinoma. This study is designed to investigate the affect of aldosterone on the mitochondrial function, specifically fatty acid ...
Oxidative stress-mediated mitochondrial dysfunction contributes to angiotensin II-induced nonalcoholic fatty liver disease in transgenic ren2 rats

Wei, Yongzhong; Clark, Suzanne E.; Thyfault, John P.; Uptergrove, Grace M.E.; Wenhan, Li; Whaley-Connell, Adam T.; Ferrario, Carlos M.; Sowers, James R. (James Russell), 1942-; Ibdah, Jamal A. (American Society for Investigative Pathology, 2009)

Emerging evidence indicates that impaired mitochondrial fatty acid [beta]-oxidation plays a key role in liver steatosis. We have recently demonstrated that increased angiotensin (ANG) II causes progressive hepatic steatosis ...