• Does stimulant therapy help adult ADHD? 

    Lutton, Michelle E.; Leach, Laura (Family Physicians Inquiries Network, 2003)
    Central nervous system stimulants improve symptoms of attention deficit-hyperactivity disorder (ADHD) in adults (strength of recommendation: B, based on an older, inconclusive systematic review, a lesser-quality systematic ...
  • In menopausal women, does fatigue indicate disease? 

    Hall, Mary N.; Leach, Laura (Family Physicians Inquiries Network, 2005)
    Though fatigue is a commonly reported symptom, high-quality studies evaluating it as a marker for diseases among menopausal women are lacking. Middle-aged women who report fatigue are more apt to screen positive for clinical ...
  • Is methylphenidate useful for treating adolescents with ADHD? 

    Mott, Timothy F.; Leach, Laura (Family Physicians Inquiries Network, 2004)
    Methylphenidate (Ritalin) is effective in the shortterm treatment of attention deficit/hyperactivity disorder (ADHD) (strength of recommendation [SOR]: A, multiple randomized control trials). Though the immediate-release ...
  • Management of Cervical Lymphadenitis in Children 

    Dulin, Michael F.; Kennard, Timothy P.; Leach, Laura (Family Physicians Inquiries Network, 2008)
    Cervical lymphadenitis, defined as an acute symptomatic enlargement of the cervical lymph nodes, is a common condition in children of all ages. Most cases of cervical lymphadenitis in children are self-limited and can ...
  • Should the varicella vaccine be given to all children to prevent chickenpox? 

    Plescia, Marcus; Leach, Laura; Rundell, Kristen (Family Physicians Inquiries Network, 2004)
    Healthy, unimmunized children who have not had varicella infection should be vaccinated (strength of recommendation: A, based on randomized controlled trials). Use of the vaccine in immunocompromised children is still being ...
  • Treatment of Bulimia Nervosa 

    Hall, Mary N.; Friedman, R. Joseph II; Leach, Laura (Family Physicians Inquiries Network, 2008)
    Cognitive behavior therapy (CBT) is the most effective treatment for bulimia nervosa based on multiple consistent randomized-controlled trials (RCTs). (Strength of Recommendation [SOR]: A). Guided self-help has not been ...
  • What illnesses contraindicate immunization? 

    Plescia, Marcus; Leach, Laura (Family Physicians Inquiries Network, 2005)
    The Advisory Council on Immunization Practices (ACIP) reports that the only contraindication for all vaccines is a history of severe allergic reaction to a previous vaccine or vaccine constituent (strength of recommendations: ...
  • What is the best treatment for analgesic rebound headaches? 

    McPherson, Vanessa; Leach, Laura (Family Physicians Inquiries Network, 2005)
    Abrupt discontinuation of the offending analgesic(s), and treating rebound headaches with dihydroergotamine (DHE) as needed, results in significant improvement for most patients (strength of recommendation [SOR]: C; based ...
  • Which blood tests are most helpful in evaluating pelvic inflammatory disease? 

    Hall, Mary N.; Leach, Laura (Family Physicians Inquiries Network, 2004)
    No individual or combination of blood tests can reliably diagnose pelvic inflammatory disease (PID)(strength of recommendation [SOR]: A, metaanalysis). The combination of white blood cell count, C-reactive protein (CRP), ...