Browsing by Author/Contributor "Lu, Yuan"

Now showing items 1-3 of 3

Can estrogen related receptor cure cancer? [abstract]

Lu, Yuan (2010-02)

Orphan nuclear receptor estrogen related receptors (ERRs) share high homology with estrogen receptor(ER), and transcription co-activators. ERRs are constitutively activated without estrodiol binding. ERRs involve in ...
Characterization of Esrrb function in metastatic prostate cancer cells and transcriptional regulation of hedgehog-signaling pathway target genes

Lu, Yuan (University of Missouri--Columbia, 2014)

Orphan nuclear receptor Estrogen Receptor Related Receptor Beta (Esrrb) is a transcription factor. Although it was also shown to be important in cancer, little is known about its function in cancer cells and cancer relevant ...
Estrogen receptor and estrogen related receptor may corporatley regulate hypoxic gene expression [abstract]

Lu, Yuan (2010-03)

Tumor cells can undergo adaptation to the hypoxia environment created by rapid growth of tumor cells to persist growing. A main regulator of hypoxia induced gene expression is hypoxia-inducible factor (HIF), and HIF can ...