Browsing by Author/Contributor "Rold, Tammy L."

Now showing items 1-8 of 8

  • 99mTc-DPR-SSS-BBN for diagnosis of human cancers [abstract] 

    Heinzke, Laura; Retzloff, Lauren Brooke, 1980-; Lane, Stephanie R., 1982-; Prasanphanich, Adam; Sieckman, Gary; Rold, Tammy L.; Hoffman, Timothy Joseph, 1958-; Smith, Charles J. (Charles Jeffrey), 1969- (University of Missouri--Columbia. Office of Undergraduate Research, 2008)
    Receptor-specific, radiolabeled peptides have become increasingly popular as targeting vectors for the development of new diagnostic radiopharmaceuticals. The over-expression of certain receptors such as the gastrin releasing ...

  • Evaluation of a new series of copper-64-nota-bombesin targeted radiopharmecuticals with PET imaging potential [abstract] 

    Prasanphanich, Adam; Nanda, Prasant Kumar; Rold, Tammy L.; Hoffman, Timothy Joseph, 1958-; Smith, Charles J. (Charles Jeffrey), 1969- (University of Missouri--Columbia. Office of Undergraduate Research, 2007)
    Tissue-specific radiopharmaceuticals having promise as diagnostic and therapeutic targeting vectors for human cancers is of significant interest. In recent years, our group and many others have focused upon design and ...

  • In vitro/in vivo assessment of novel 99mTc-bombesin conjugates in human cancer tissue [abstract] 

    Heinzke, Laura; Prasanphanich, Adam; Lane, Stephanie R., 1982-; Retzloff, Lauren Brooke, 1980-; Rold, Tammy L.; Sieckman, Gary; Hoffman, Timothy Joseph, 1958-; Smith, Charles J. (Charles Jeffrey), 1969- (University of Missouri--Columbia. Office of Undergraduate Research, 2007)
    Receptor-specific, radiolabeled peptides are becoming increasingly popular as targeting vectors for the development of new diagnostic radiopharmaceuticals. The over-expression of certain receptors such as the gastrin ...

  • The magic bullet: Creating Indium-111 bombesin targeting vectors for use in diagnostic imaging of prostate and breast cancer [abstract] 

    Cook, Benjamin; Garrison, Jered C.; Bottenus, Brienne N., 1984-; Sieckman, Gary; Rold, Tammy L.; Shelton, Tiffani; Hoffman, Timothy Joseph, 1958- (University of Missouri--Columbia. Office of Undergraduate Research, 2007)
    Background: According to the American Cancer Society, over 68,000 men and women will die from prostate and breast cancer in this year alone. Prostate, breast and other cancers have been shown to express the BB2 receptor. ...

  • Overexpression of the RNA-binding protein HuR impairs tumor growth in triple negative breast cancer associated with deficient angiogenesis [abstract] 

    Gubin, Matthew M.; Calaluce, Robert; Davis, J. Wade; Magee, Joseph D.; Strouse, Connie S.; Shaw, Daniel P.; Hoffman, Timothy Joseph, 1958-; Rold, Tammy L. (2010)
    Breast cancer is the second most common cancer in women and causes the death of 519,000 people worldwide. Many cancer genes are posttranscriptionally regulated by RNA-binding proteins (RBPs) and microRNAs. The RBP HuR binds ...

  • Performancee evaluation of a dual Micro-SPECT detector system [abstract] 

    Walters, Andrew; Daibes Figueroa, Said, 1977-; Rold, Tammy L.; Hoffman, Timothy Joseph, 1958- (University of Missouri--Columbia. Office of Undergraduate Research, 2006)
    The ability to conduct radiopharmaceutical research in vivo is largely dependent on nuclear imaging hardware and is subject to its limitations. The inability of clinical instrumentation to conduct non-invasive tracer ...

  • Targeting the BB2 receptor on human prostate cancer cells using Indium-111 labeled radiopharmaceutical [abstract] 

    Naz, Farah; Garrison, Jered C.; Rold, Tammy L.; Sieckman, Gary; Carter, Sara; Bell, N. R.; Daibes Figueroa, Said, 1977-; Walters, Andrew; Hoffman, Timothy Joseph, 1958- (University of Missouri--Columbia. Office of Undergraduate Research, 2006)
    The BB2 receptor, belonging to the Bombesin receptor family, has been shown to be highly over expressed in a variety of cancer cell lines, including human prostate cancer. Over expression of the BB2 receptor offers an ...

  • Using Indium-111 labeled radiopharmaceuticals to target the BB2 receptor on human prostate cancer cells [abstract] 

    Naz, Farah; Garrison, Jered C.; Rold, Tammy L.; Sieckman, Gary; Carter, Sara; Bell, N. R.; Figueroa, Said Daibes; Walters, Andrew; Hoffman, Timothy Joseph, 1958- (University of Missouri--Columbia. Office of Undergraduate Research, 2007)
    The BB2 receptor, belonging to the Bombesin receptor family, has been shown to be highly over expressed in a variety of cancer cell lines, including human prostate cancer. Our laboratory have been involved, for over a ...