Browsing by Author/Contributor "Ruhlen, Rachel L."

Now showing items 1-7 of 7

  • Benefits of soy-based feeds for fetal estrogen levels and obesity in adulthood 

    Kirkpatrick, James R., 1983-; Ruhlen, Rachel L.; vom Saal, Frederick S. (University of Missouri--Columbia. Office of Undergraduate Research, 2004)
    We examined the effect of maternal exposure to naturally occurring estrogenic chemicals in diets on circulating levels of estradiol in mouse fetuses. An animal's specific response to estrogen can vary according to the time ...

  • Bisphenol A Is Released from Used Polycarbonate Animal Cages into Water at Room Temperature 

    Howdeshell, Kembra L. (Kembra Lynne), 1968-; Peterman, Paul Herbert, 1948-; Judy, Barbara M.; Taylor, Julia A.; Orazio, Carl E.; Ruhlen, Rachel L.; vom Saal, Frederick S.; Welshons, Wade V. (Environmental Health Perspectives, 2003)
    Bisphenol A (BPA) is a monomer with estrogenic activity that is used in the production of food packaging, dental sealants, polycarbonate plastic, and many other products. The monomer has previously been reported to hydrolyze ...

  • Estradiol and Bisphenol A Stimulate Androgen Receptor and Estrogen Receptor Gene Expression in Fetal Mouse Prostate Mesenchyme Cells 

    Richter, Catherine A.; Taylor, Julia A.; Ruhlen, Rachel L.; vom Saal, Frederick S. (Environmental Health Perspectives, 2007)
    Hormonal alterations during development have lifelong effects on the prostate gland. Endogenous estrogens, including 17β-estradiol (E2), and synthetic estrogenic endocrine disruptors, such as bisphenol A (BPA), have similar ...

  • An estrogen induced, estrogen responsive rat model of breast cancer [abstract] 

    Willbrand, Dana M.; Ruhlen, Rachel L.; Besch-Williford, Cynthia Lee, 1954-; Shull, James D.; Sauter, Edward R. (University of Missouri--Columbia. Office of Undergraduate Research, 2008)
    Because women experience a bewildering array of chemicals, foods and lifestyles, only profound effects on preventing or promoting breast cancer are detectible in human studies. Subtle or delayed effects can be detected in ...

  • A human relevant rat model of breast cancer [abstract] 

    Willbrand, Dana M.; Sauter, Edward R.; Ruhlen, Rachel L. (University of Missouri--Columbia. Office of Undergraduate Research, 2007)
    Estrogen receptor (ER) status is an important prognostic factor of human breast cancer. ER+ breast cancers, which make up 95% of human breast cancers, have a good prognosis because the growth of these tumors is dependent ...

  • A human relevent rat model of breast cancer 

    Willbrand, Dana M.; Besch-Williford, Cynthia Lee, 1954-; Ma, Lixin; Shull, James D.; Sauter, Edward R.; Ruhlen, Rachel L. (University of Missouri--Columbia. Office of Undergraduate Research, 2008)
    Because women experience a bewildering array of chemicals, foods and lifestyles, only profound effects on preventing or promoting breast cancer are detectible in human studies. Subtle or delayed effects can be detected in ...

  • Low Phytoestrogen Levels in Feed Increase Fetal Serum Estradiol Resulting in the “Fetal Estrogenization Syndrome” and Obesity in CD-1 Mice 

    Ruhlen, Rachel L.; Howdeshell, Kembra L. (Kembra Lynne), 1968-; Mao, Jiude; Taylor, Julia A.; Bronson, F. H.; Newbold, Retha R.; Welshons, Wade V.; vom Saal, Frederick S. (Environmental Health Perspectives, 2008)
    Although estrogenic chemicals can disrupt development of the reproductive system, there is debate about whether phytoestrogens in soy are beneficial, benign, or harmful. We compared reproductive and metabolic characteristics ...