Browsing by Author/Contributor "Shortt, Katherine Anne"

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Identification of novel coding single nucleotide polymorphisms associated with acute respiratory distress syndrome

Shortt, Katherine Anne (2014-07-28)

ARDS is a lung condition characterized by impaired gas exchange with systemic release of inflammatory mediators, causing inflammation, hypoxemia and multiple organ failure. Disease susceptibility and progression are poorly ...
Identification of Novel Regulatory Genes in Acetaminophen Induced Hepatocyte Toxicity by a Genome-Wide CRISPR/Cas9 Screen

Shortt, Katherine Anne (University of Missouri -- Kansas City, 2018)

Acetaminophen (APAP) is a commonly used analgesic responsible for over 56,000 overdose-related emergency room visits annually. A long asymptomatic period and limited treatment options result in a high rate of liver ...