Browsing by Author/Contributor "Stigleman, Sue"
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Antiepileptic Drug Level Monitoring
Malaty, Wail; Stigleman, Sue (Family Physicians Inquiries Network, 2008)Routine monitoring of antiepileptic drug levels does not alter seizure or side effect rates. (Strength of Recommendation [SOR]: B, based on a single randomized controlled trial [RCT] with less than 80 percent follow-up). ... -
Can calcium supplements cause serious adverse effects in healthy people?
Shaker, Hayam K.; Stigleman, Sue (Family Physicians Inquiries Network, 2012)Calcium supplements with or without vitamin D increase the risk of myocardial infarction (MI), with numbers needed to harm (NNH) over 5 years of 69 to 240 (strength of recommendation [SOR]: B, meta-analyses of randomized ... -
Does surgery relieve the pain of a herniated disc?
Sorensen, Betsey; Hulkower, Stephen D.; Stigleman, Sue (Family Physicians Inquiries Network, 2010)Patients with an acute episode of low back pain, radicular symptoms, and evidence of a herniated disc on imaging may experience short-term pain relief from discectomy if their symptoms haven�۪t improved after initial ... -
Does XR injectable naltrexone prevent relapse as effectively as daily sublingual buprenorphine-naloxone?
Roe, Matthew; Wilson, Courtenay Gilmore; Fusco, Carriedelle Wilson; Hulkower, Stephen; Stigleman, Sue (Family Physicians Inquiries Network, 2020)Q: Does XR injectable naltrexone prevent relapse as effectively as daily sublingual buprenorphine-naloxone? Evidence-based answer: Yes. Monthly extended-release injectable naltrexone (XR-NTX) treats opioid use disorder as ... -
Effect of corticosteroids on pain and function in knee osteoarthritis patients
Beggs, Luke; Stigleman, Sue; Vaughan, Aaron; Pacious, Josh; Hulkower, Stephen (Family Physicians Inquiries Network, 2020)Clinical Inquiries question: Does the type of corticosteroid have an effect on pain and functional status of the knee in osteoarthritis (OA) patients receiving intra-articular injections? Evidence-based answer: In patients ... -
How often does long-term PPI therapy cause clinically significant hypomagnesemia?
Plaut, Timothy; Graeme, Katelyn; Stigleman, Sue; Hulkower, Stephen; Woodall, Tasha (Family Physicians Inquiries Network, 2018)Q: How often does long-term PPI therapy cause clinically significant hypomagnesemia? EVIDENCE-BASED ANSWER: Rarely. Proton pump inhibitors (PPIs) may be associated with decreases in serum magnesium laboratory values to ... -
Is the long-term use of proton pump inhibitors safe?
Malaty, Wail; Stigleman, Sue; Mayer, Jill Byerly (Family Physicians Inquiries Network, 2004)Long-term use of proton pump inhibitors (PPIs) appears safe, resulting in no clinically relevant adverse effects (strength of recommendation: B, based on nonsystematic reviews, cohort studies, or low-quality randomized ... -
Should we discontinue Pap smear screening in women aged >65 years?
Curran, Diana Renee; Stigleman, Sue (Family Physicians Inquiries Network, 2004)Women with a history of regular, normal Pap smear screening should discontinue screening by age 65 years (strength of recommendation [SOR]: B). Women without a history of serial normal Pap smears should continue screening ... -
Should you evaluate for CAD in seniors with premature ventricular contractions?
Nobles, Michelle B.; Langlois, John P.; Stigleman, Sue (Family Physicians Inquiries Network, 2008)Current guidelines suggest evaluating patients with premature ventricular contractions (PVCs) and associated risk factors for underlying coronary artery disease (strength of recommendation [SOR]: C, expert opinion). -
What are the benefits and risks of daily low-dose aspirin for primary prevention of CV events?
Mutter, Justin; Grandy, Rebecca; Hulkower, Stephen; Stigleman, Sue (Family Physicians Inquiries Network, 2018)Q: What are the benefits and risks of daily low-dose aspirin for primary prevention of CV events? A: One nonfatal myocardial infarction (MI) will be avoided for every 126 to 138 adults who take daily aspirin for 10 years ... -
What is the best hypnotic for use in the elderly?
Scott, Mollie Ashe; Stigleman, Sue (Family Physicians Inquiries Network, 2003)Short-acting hypnotics such as zolpidem (Ambien) or zaleplon (Sonata) are the preferred hypnotics in the elderly because of an improved side-effect profile compared with traditional hypnotics such as benzodiazepines (strength ... -
What is the differential diagnosis of chronic diarrhea in immunocompetent patients?
Kruszka, Paul S.; Stigleman, Sue (Family Physicians Inquiries Network, 2002)Case series from tertiary-care centers report toddler's diarrhea, cow's milk sensitivity enteropathy, infection, celiac disease, and idiopathic chronic diarrhea as the most common etiologies in the pediatric population. ... -
What regimens eradicate Heliobacter pylori?
Malaty, Wail; Stigleman, Sue (Family Physicians Inquiries Network, 2003)Fourteen-day triple therapy with a proton pump inhibitor (PPI) plus clarithromycin and either amoxicillin or metronidazole is superior to 7-day therapy in eradicating Heliobacter pylori (strength of recommendation [SOR]: ... -
Which oral nonopioid agents are most effective for OA pain?
Gilmer, Benjamin; Hulkower, Stephen; Wilson, Courtenay Gilmore; Macdonald, Brittney; Pozner, Jonathan; Stigleman, Sue (Family Physicians Inquiries Network, 2019)Q Which oral nonopioid agents are most effective for OA pain? Evidence-based answer: nonsteroidal anti-inflammatory drugs (nsaids), when used at the maximum clinically effective dose, reduce osteoarthritis (OA) pain in ...