Now showing items 1-14 of 14

  • Antiepileptic Drug Level Monitoring 

    Malaty, Wail; Stigleman, Sue (Family Physicians Inquiries Network, 2008)
    Routine monitoring of antiepileptic drug levels does not alter seizure or side effect rates. (Strength of Recommendation [SOR]: B, based on a single randomized controlled trial [RCT] with less than 80 percent follow-up). ...
  • Can calcium supplements cause serious adverse effects in healthy people? 

    Shaker, Hayam K.; Stigleman, Sue (Family Physicians Inquiries Network, 2012)
    Calcium supplements with or without vitamin D increase the risk of myocardial infarction (MI), with numbers needed to harm (NNH) over 5 years of 69 to 240 (strength of recommendation [SOR]: B, meta-analyses of randomized ...
  • Does surgery relieve the pain of a herniated disc? 

    Sorensen, Betsey; Hulkower, Stephen D.; Stigleman, Sue (Family Physicians Inquiries Network, 2010)
    Patients with an acute episode of low back pain, radicular symptoms, and evidence of a herniated disc on imaging may experience short-term pain relief from discectomy if their symptoms haven�۪t improved after initial ...
  • Does XR injectable naltrexone prevent relapse as effectively as daily sublingual buprenorphine-naloxone? 

    Roe, Matthew; Wilson, Courtenay Gilmore; Fusco, Carriedelle Wilson; Hulkower, Stephen; Stigleman, Sue (Family Physicians Inquiries Network, 2020)
    Q: Does XR injectable naltrexone prevent relapse as effectively as daily sublingual buprenorphine-naloxone? Evidence-based answer: Yes. Monthly extended-release injectable naltrexone (XR-NTX) treats opioid use disorder as ...
  • Effect of corticosteroids on pain and function in knee osteoarthritis patients 

    Beggs, Luke; Stigleman, Sue; Vaughan, Aaron; Pacious, Josh; Hulkower, Stephen (Family Physicians Inquiries Network, 2020)
    Clinical Inquiries question: Does the type of corticosteroid have an effect on pain and functional status of the knee in osteoarthritis (OA) patients receiving intra-articular injections? Evidence-based answer: In patients ...
  • How often does long-term PPI therapy cause clinically significant hypomagnesemia? 

    Plaut, Timothy; Graeme, Katelyn; Stigleman, Sue; Hulkower, Stephen; Woodall, Tasha (Family Physicians Inquiries Network, 2018)
    Q: How often does long-term PPI therapy cause clinically significant hypomagnesemia? EVIDENCE-BASED ANSWER: Rarely. Proton pump inhibitors (PPIs) may be associated with decreases in serum magnesium laboratory values to ...
  • Is the long-term use of proton pump inhibitors safe? 

    Malaty, Wail; Stigleman, Sue; Mayer, Jill Byerly (Family Physicians Inquiries Network, 2004)
    Long-term use of proton pump inhibitors (PPIs) appears safe, resulting in no clinically relevant adverse effects (strength of recommendation: B, based on nonsystematic reviews, cohort studies, or low-quality randomized ...
  • Should we discontinue Pap smear screening in women aged >65 years? 

    Curran, Diana Renee; Stigleman, Sue (Family Physicians Inquiries Network, 2004)
    Women with a history of regular, normal Pap smear screening should discontinue screening by age 65 years (strength of recommendation [SOR]: B). Women without a history of serial normal Pap smears should continue screening ...
  • Should you evaluate for CAD in seniors with premature ventricular contractions? 

    Nobles, Michelle B.; Langlois, John P.; Stigleman, Sue (Family Physicians Inquiries Network, 2008)
    Current guidelines suggest evaluating patients with premature ventricular contractions (PVCs) and associated risk factors for underlying coronary artery disease (strength of recommendation [SOR]: C, expert opinion).
  • What are the benefits and risks of daily low-dose aspirin for primary prevention of CV events? 

    Mutter, Justin; Grandy, Rebecca; Hulkower, Stephen; Stigleman, Sue (Family Physicians Inquiries Network, 2018)
    Q: What are the benefits and risks of daily low-dose aspirin for primary prevention of CV events? A: One nonfatal myocardial infarction (MI) will be avoided for every 126 to 138 adults who take daily aspirin for 10 years ...
  • What is the best hypnotic for use in the elderly? 

    Scott, Mollie Ashe; Stigleman, Sue (Family Physicians Inquiries Network, 2003)
    Short-acting hypnotics such as zolpidem (Ambien) or zaleplon (Sonata) are the preferred hypnotics in the elderly because of an improved side-effect profile compared with traditional hypnotics such as benzodiazepines (strength ...
  • What is the differential diagnosis of chronic diarrhea in immunocompetent patients? 

    Kruszka, Paul S.; Stigleman, Sue (Family Physicians Inquiries Network, 2002)
    Case series from tertiary-care centers report toddler's diarrhea, cow's milk sensitivity enteropathy, infection, celiac disease, and idiopathic chronic diarrhea as the most common etiologies in the pediatric population. ...
  • What regimens eradicate Heliobacter pylori? 

    Malaty, Wail; Stigleman, Sue (Family Physicians Inquiries Network, 2003)
    Fourteen-day triple therapy with a proton pump inhibitor (PPI) plus clarithromycin and either amoxicillin or metronidazole is superior to 7-day therapy in eradicating Heliobacter pylori (strength of recommendation [SOR]: ...
  • Which oral nonopioid agents are most effective for OA pain? 

    Gilmer, Benjamin; Hulkower, Stephen; Wilson, Courtenay Gilmore; Macdonald, Brittney; Pozner, Jonathan; Stigleman, Sue (Family Physicians Inquiries Network, 2019)
    Q Which oral nonopioid agents are most effective for OA pain? Evidence-based answer: nonsteroidal anti-inflammatory drugs (nsaids), when used at the maximum clinically effective dose, reduce osteoarthritis (OA) pain in ...