Browsing by Author/Contributor "Wei, Yongzhong"

Now showing items 1-3 of 3

  • Attenuation of NADPH Oxidase Activation and Glomerular Filtration Barrier Remodeling With Statin Treatment 

    Whaley-Connell, Adam T.; Habibi, Javad, 1947-; Nistala, Ravi; Cooper, Shawna A.; Karuparthi, Poorna R.; Hayden, Melvin; DeMarco, Vincent G.; Andresen, Bradley T.; Wei, Yongzhong; Ferrario, Carlos M.; Sowers, James R. (James Russell), 1942- (American Heart Association, Inc., 2008)
    Activation of reduced nicotinamide-adenine dinucleotide phosphate (NADPH) oxidase by angiotensin II is integral to the formation of oxidative stress in the vasculature and the kidney. 3-Hydroxy-3-methylglutaryl-coenzyme A ...

  • Mineralocorticoid receptor antagonism attenuates vascular apoptosis and injury via rescuing protein kinase B activation 

    Wei, Yongzhong; Whaley-Connell, Adam T.; Habibi, Javad, 1947-; Rehmer, Jenna; Rehmer, Nathan; Patel, Kamlesh D.; Hayden, Melvin; DeMarco, Vincent G.; Ferrario, Carlos M.; Ibdah, Jamal A.; Sowers, James R. (James Russell), 1942- (American Heart Association, 2008)
    Emerging evidence indicates that mineralocorticoid receptor (MR) blockade reduces the risk of cardiovascular events beyond those predicted by its blood pressure-lowering actions; however, the underlying mechanisms remain ...

  • Oxidative stress-mediated mitochondrial dysfunction contributes to angiotensin II-induced nonalcoholic fatty liver disease in transgenic ren2 rats 

    Wei, Yongzhong; Clark, Suzanne E.; Thyfault, John P.; Uptergrove, Grace M.E.; Wenhan, Li; Whaley-Connell, Adam T.; Ferrario, Carlos M.; Sowers, James R. (James Russell), 1942-; Ibdah, Jamal A. (American Society for Investigative Pathology, 2009)
    Emerging evidence indicates that impaired mitochondrial fatty acid [beta]-oxidation plays a key role in liver steatosis. We have recently demonstrated that increased angiotensin (ANG) II causes progressive hepatic steatosis ...