Browsing by Thesis Department "Biomedical Sciences (MU)"
Now showing items 1-17 of 17
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Assessment of tibial morphologic alterations following correction of excessive tibial plateau angle in dogs
(University of Missouri--Columbia, 2023)Given the frequent addition of new techniques used to address cases of cranial cruciate ligament disease with excessive tibial plateau angle (eTPA), we sought to document the effect of popular surgical methods used to treat ... -
Bacterial culture and susceptibility of samples taken from septic foot lesions of adult beef cattle
(University of Missouri--Columbia, 2021)Lameness is an economically important and common disease of cattle. Foot disease is the most common cause of cattle lameness; however, there are few publications regarding lameness in cow-calf operations. The objectives ... -
The canine ocular surface microbiota
(University of Missouri--Columbia, 2020)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Next generation sequencing (NGS) has been used to identify a diverse ocular surface (OS) microbiota in many species, highlighting limitations in ... -
Cardiac biomarkers (NT-proBNP and cardiac troponin-I) and point-of-care ultrasound in dogs with cardiac and non-cardiac causes of non-hemorrhagic ascites
(University of Missouri--Columbia, 2023)Background: Non-hemorrhagic ascites (NHA) can be caused by cardiac diseases (cNHA) and non-cardiac diseases (ncNHA). N-terminal brain natriuretic peptide (NT-proBNP), cardiac troponin-I (cTnI) and point-of-care ultrasound ... -
Characterization of the impact of platelet-rich plasma and corticosteroid upon clinical and biochemical outcomes of knee osteoarthritis patients
(University of Missouri--Columbia, 2023)Introduction: There is no cure for symptomatic knee osteoarthritis (OA), and intra-articular injection is frequently used to provide symptomatic relief for patients of this debilitating disease. This study was performed ... -
Diagnosis of aerodigestive disorders in dogs utilizing videofluoroscopic swallow study
(University of Missouri--Columbia, 2022)[EMBARGOED UNTIL 12/1/2023] An aerodigestive disease (AeroD) is a disorder pathologically linking the respiratory and alimentary tracts. Dogs having respiratory signs without dysphagia, vomiting, or regurgitation typically ... -
Evaluation of a relatively hyperosmolar irrigation solution for use in equine femorotibial arthroscopy
(University of Missouri--Columbia, 2022)Hyperosmolar irrigation solutions have been shown to decrease fluid extravasation during arthroscopic procedures and safety has been demonstrated in canine and human studies. Prospective, blinded, randomized controlled ... -
Evaluation of incisional gastropexy modified by addition of two full-thickness stomach to body wall sutures for prevention of gastric dilatation-volvulus
(University of Missouri--Columbia, 2023)Gastric dilatation-volvulus (GDV) is a common disease in large breed dogs. Its treatment involves medical management and surgical reposition of the stomach. To prevent the occurrence or recurrence of GDV, gastropexy is ... -
Fetoscopic in utero tracheal occlusion as a method to reduce fetal lung hypoplasia in a sheep model of congenital diaphragmatic hernia
(University of Missouri--Columbia, 2023)[EMBARGOED UNTIL 5/1/2024] Congenital diaphragmatic hernia (DH) is a potentially fatal malformation that occurs in 1/2500 human births. Pulmonary hypoplasia decreases survival rate due to compression of thoracic contents ... -
Intramammary infections in lactating Jersey cows: prevalence of pathogens and association of pathogen type with milk somatic cell count and persistence of infection
(University of Missouri--Columbia, 2022)[EMBARGOED UNTIL 8/1/2023] There is limited data available regarding pathogens causing intramammary infections (IMI) in Jersey cows. The objectives of this study were to characterize the prevalence of IMI caused by different ... -
Neonatal beef calf morbidity and mortality in Missouri
(University of Missouri--Columbia, 2022)[EMBARGOED UNTIL 12/1/2023] Neonatal morbidity and mortality are major causes of economic loss for US beef cattle producers. The Missouri cattle industry represents 19 percent of the total agriculture sales in the state ... -
Prospective evaluation of the fecal microbiome in dogs with large-cell lymphoma receiving chop chemotherapy
(University of Missouri--Columbia, 2021)The fecal microbiome composition has been associated with reduced efficacy of cancer therapy and adverse side effects in humans, and chemotherapy has been shown to alter the gut microbiome. The relationship between microbiota ... -
A quantitative evaluation of DNA damage from irradiation of feline oral squamous cell carcinoma cells
(University of Missouri--Columbia, 2022)Feline oral squamous cell carcinoma is a locally invasive neoplasm that continues to carry a poor prognosis despite advances in multimodality oncologic treatment. Location, completeness of surgical excision or complete ... -
Relative HER2 protein expression in normal canine tissue and canine osteosarcoma
(University of Missouri--Columbia, 2022)Development of HER2-targeted immunotherapy in canine osteosarcoma (OSA) is underway, yet HER2 expression in normal and neoplastic canine tissue has not yet been defined. This study's objective was to evaluate the relative ... -
The role of Cdc42 Rho GTPase in the cystic fibrosis intestinal epithelial barrier
(University of Missouri--Columbia, 2022)Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. People with CF and CF mouse models experience increased intestinal permeability, but the molecular mechanisms ... -
Topical therapeutic strategies for the treatment of corneal fibrosis in veterinary species
(University of Missouri--Columbia, 2022)Purpose: To determine the safety and efficacy of a novel combination of TRAM-34 and ascorbic acid applied topically in vivo in native and alkali injured rabbit corneas. Methods: Twelve New Zealand rabbits were randomly ... -
Using probiotics to modulate the asthmatic phenotype, respiratory microbiota, and immune responses in cats
(University of Missouri--Columbia, 2023)[EMBARGOED UNTIL 5/1/2024] Feline asthma is associated with respiratory dysbiosis, correction of which could serve as novel treatment. We hypothesized that in asthmatic cats treated with anti-inflammatory glucocorticoids, ...