Browsing by Title "A BAC transgene expressing human CFTR under control of its regulatory elements rescues Cftr knockout mice"
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A BAC transgene expressing human CFTR under control of its regulatory elements rescues Cftr knockout mice
(Nature Publishing Group, 2019)Small-molecule modulators of cystic fibrosis transmembrane conductance regulator (CFTR) biology show promise in the treatment of cystic fibrosis (CF). A Cftr knockout (Cftr KO) mouse expressing mutants of human CFTR would ...