• Mechanisms of clostridial neurotoxin binding and entry 

    Burns, Joshua R. (University of Missouri--Columbia, 2016)
    The botulinum neurotoxins (BoNTs) and tetanus neurotoxin (TeNT) make up the clostridial neurotoxin (CNT) family. The CNTs are produced by Clostridium botulinum and Clostridum tetani respectively, and are the most potent ...
  • Mechanisms of clostridial toxin binding and translocation 

    Lambert, Gregory Stephen (University of Missouri--Columbia, 2018)
    The bacterial genus Clostridium consists of over 150 species of anaerobic, fermentative, spore-forming bacilli. Clostridial species produce up to 20% of all known bacterial exotoxins, which serve as important virulence ...
  • Structural and functional characterization of Clostridium difficile toxin B binding and entry 

    Manse, Jared Stephen, 1981- (University of Missouri--Columbia, 2016)
    Clostridium difficile (C. difficile) has recently emerged as a worldwide nosocomial and iatrogenic infection. C. difficile is a gram-positive, motile bacillus whose sporulation ability significantly contributes to its ...