Browsing by Thesis Advisor "Beamer, Lesa J. (Lesa Jean)"
Now showing items 1-4 of 4
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Molecular mechanisms of enzyme dysfunction in human phosphoglucomutase-1 deficiency
(University of Missouri--Columbia, 2019)Human phosphoglucomutase-1 (PGM1) belongs to the [alpha]-D-phosphohexomutase superfamily, an ancient lineage of enzymes critical for carbohydrate metabolism. PGM1 catalyzes the interconversion of glucose-1-phosphate and ... -
Stability, states, and interactions of the enzyme PMM/PGM by NMR and multivariate analysis
(University of Missouri--Columbia, 2016)Phosphomannomutase/phosphoglucomutase (PMM/PGM) contributes to the infectivity of an opportunistic human pathogen Pseudomonas aeruginosa by participating in carbohydrate biosynthesis. As a phospho-transfer enzyme, PMM/PGM ... -
Structural studies of PMM/PGM from Pseudomonas aeruginosa
(University of Missouri--Columbia, 2005)The human pathogen Pseudomonas aeruginosa expresses a variety of cell surface polysaccharides, including alginate, lipopolysaccharide (LPS), and rhamnolipid. P. aeruginosa is the primary cause of chronic lung infections ... -
Structure, dynamics, evolution and catalysis of phosphohexomutase from Pseudomonas aeruginosa
(University of Missouri--Columbia, 2013)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] [alpha]-D phosphohexomutases are ubiquitous in the environment and participate in carbohydrate metabolism by catalyzing an intramolecular phosphoryl ...