Browsing by Thesis Department "Cellular and Molecular Biology (UMKC)"
Now showing items 1-5 of 5
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A single molecule study on the structural basis of ion selective permeation in voltage-gated sodium channels
(2021)High resolution studies of voltage-gated sodium channels (VGSCs) can not reveal the dynamic nature of the channel structures, especially in lipid environments, which are vital for rational drug design. The bacterial NavAb ... -
Alterations in cardiac contractility and heart rate mediated by bone loading
(2022)The skeleton is a dynamic organ in complex interplay with the other systems of the body and is highly responsive to input from the external environment. Increasingly, evidence is mounting that the skeleton is the source ... -
Expression Pattern of Drug-Resistance Genes in Matched Clinical Isolates of Candida albicans at Variable Fluconazole Exposure Times
(2016)Candida albicans is an opportunistic fungus that exists naturally in the vaginal, urinary, and gastrointestinal tracts of humans. Typically, this yeast remains balanced with the body’s other natural microbial flora and the ... -
The Middle Region is Required for Phosphorylation Regulation of Ceramide Transfer Protein
(2013)The trafficking of ceramide from endoplasmic reticulum (ER), where it is synthesized, to the Golgi for sphingomyelin synthesis is mediated by the ceramide transfer protein (CERT) in a nonvesicular fashion. CERT is a cytosolic ... -
The canonical Wnt signaling pathway affects regeneration of mechanosensory hair cells in Danio Rerio
(2020)In vertebrates, mechanosensory hair cells are located in the inner ear and mediate hearing. When damage to these specialized cells occur, it leads to irreversible hearing loss. Not only do aquatic vertebrates have inner ...