Browsing by Thesis Advisor "Garcia, Michael L."
Now showing items 1-4 of 4
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Canine degenerative myelopathy : perspectives from aging, microglia and neurofilaments
(University of Missouri--Columbia, 2017)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Canine degenerative myelopathy (DM) is a late-onset neurodegenerative disease similar to some forms of amyotrophic lateral sclerosis (ALS). Mutations ... -
The characterization of the tetratricopeptide repeat protein 13 in mammals
(University of Missouri--Columbia, 2012)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Tetratricopeptide repeat domain protein 13 (TTC13) is a member of a large family of proteins known as tetratricopeptide repeat (TPR) proteins that has ... -
Molecular mechanisms of radial axonal growth : insights from analysis of neurofilament gene-targeted mice
(University of Missouri--Columbia, 2012)For the nervous system to send signals rapidly, axons must undergo growth that expands their diameter. This process is known as radial growth and is dependent upon insulating myelin that wraps around the axon and the ... -
A study of readthrough therapy for spinal muscular atrophy in a transgenic mouse model
(University of Missouri--Columbia, 2009)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Spinal Muscular Atrophy (SMA) is due to the loss of the telomeric survival motor neuron gene (SMN1) and results in degeneration of motor neurons, ...