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    Browsing by Thesis Advisor "Gu, Zezong"

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    • Administration of apocynin in drinking water ameliorates transient cerebral ischemia-induced brain damage and behavioral deficits in mice 

      Lehmidi, Tareq Mohamed Elhadi (University of Missouri--Columbia, 2012)
      [ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Acute ischemic stroke is the third leading cause of death in developed countries and the most frequent cause of permanent disability in adults worldwide. ...
    • Low-intensity blast-induced mild traumatic brain injury : linking blast physics to biological outcomes 

      Song, Hailong (University of Missouri--Columbia, 2019)
      Blast-induced mild traumatic brain injury (mTBI) is of particular concern among military personnel due to exposure to blast energy during military training and combat. The impact of primary low-intensity blast (LIB) mediated ...
    • Matrix metalloproteinase proteolysis after stroke : a surrogate indicator for early diagnosis and validation of treatment 

      Blair, Gregory; Zhang, Chunyang; Hu, Rong, 1980-; Meng, Fanjun; Chang, Mayland; Mobashery, Shahriar; Cui, Jiankun (2010)
      Matrix metalloproteinases (MMPs) are a family of endoproteaseses that have various functions from development to disease. They are also believed to play critical roles in the central nerve system for the pathogenesis of ...
    • Matrix metalloproteinase-9 : surrogate marker and therapeutic target against neurovascular impairment after cerebral ischemia 

      Chen, Shanyan (University of Missouri--Columbia, 2015)
      [ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Stroke ranks fourth among all causes of death, and acute ischemic stroke is the most common form. The neurovascular unit (NVU) describes a basic ...
    • Mechanism-based inhibition of matrix metalloproteinase-9 provides neuroprotection in a mouse model of traumatic brain injury 

      Hadass, Orr (University of Missouri--Columbia, 2012)
      [ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Traumatic brain injury (TBI) is a leading cause of death and disability in the U.S. Following an initial mechanical impact, TBI progresses to a secondary ...
    • A mouse model of embolic focal ischemic stroke for investigation of anti-thrombotic therapies 

      Hu, Rong, 1980- (University of Missouri--Columbia, 2010)
      [ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Stroke is the third leading cause of death in the United States and the major cause of adult disability. Ischemic stroke accounts for about 87 percent ...
    • Of mice and men: can MMP-9 be a biomarker and a potential target for treatment after traumatic brain injury? 

      Tomlinson, Brittany N. (University of Missouri--Columbia, 2013)
      [ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Traumatic brain injury (TBI) is a highly prevalent cause of death and disability in the US and has become a significant burden to our present healthcare ...
    • The role of cytosolic phospholipase A2 in microglial signaling pathways during neuroinflammation 

      Chuang, Dennis Yi-Lun, 1985- (University of Missouri--Columbia, 2016)
      Oxidative and nitrosative stress is known to play an important role in neurodegenerative and neuroinflammatory diseases, such as Alzheimer's disease, Parkinson's disease, ischemic[slash]hemorrhagic stroke, and traumatic ...
    • Ultrastructural damages in the brain induced by low-intensity primary blast wave : a transmission electron microscopy study on mild traumatic brain injury 

      Konan, Meleine Landry (University of Missouri--Columbia, 2018)
      [ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Explosive blast-induced mild traumatic brain injury (mTBI), a "signature wound" of recent military conflicts, commonly affects Service Members. While ...

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