Browsing by Thesis Advisor "Hoffman, Timothy Joseph, 1958-"
Now showing items 1-5 of 5
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Development of a rhodium tetrathioether bombesin analogue and investigation of cyclic and acyclic ligand systems for 105Rh(III)
(University of Missouri--Columbia, 2013)Rhodium-105 is an attractive nuclide for radiotherapeutic applications due to its nuclear properties (566 keV β-, 319 keV [19%], 306 keV [5%]) and the kinetic stability of Rhodium (III) complexes with soft sulfur donor ... -
Discrete NaI(TI) crystal detector optimization for small animal SPECT molecular imaging
(University of Missouri--Columbia, 2005)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Dual-modality imaging instrumentation has allowed the noninvasive analysis of preclinical models of human disease. A combined microSPECT/CT unit (Siemens) ... -
Investigating the bifunctional chelate approach for radiopharmaceutical development
(University of Missouri--Columbia, 2010)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Radiopharmaceuticals are drugs that contain a radioactive atom for the purpose of imaging or therapy of disease. The type of emission determines the ... -
Micro-imaging characterization of mouse models of metastasis
(University of Missouri--Columbia, 2005)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Non-invasive imaging techniques have been recently developed to characterize animal models of disease. The overarching hypothesis of this work explores ... -
Targeting the bombesin subtype 2 receptor for the diagnosis and treatment of metastatic prostate cancer
(University of Missouri--Columbia, 2010)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] In the United States, prostate cancer is the most commonly diagnosed cancer and the third leading cause of cancer related deaths in men. With early ...