Browsing by Title "Inhibition Mechanism of EFdA, a Highly Potent Inhibitor of HIV Reverse Transcriptase [abstract]"

Now showing items 1-1 of 1

  • Inhibition Mechanism of EFdA, a Highly Potent Inhibitor of HIV Reverse Transcriptase [abstract] 

    Michailidis, Eleftherios; Marchand, Bruno; Kodama, Eiichi N.; Singh, Kamlendra; Kirby, Karen, 1979-; Ong, Yee T.; Ryan, Emily M.; Nagy, Eva; Ashida, Noriyuki; Murphey-Corb, Mickey; Mitsuya, Hiroaki; Parniak, Michael A.; Sarafianos, Stefan G. (2010-02)
    The nucleoside 4'-ethynyl-2-fluoro-deoxyadenosine (EFdA) is one of the most potent antiretroviral nucleosides yet described, inhibiting replication of wild-type and multidrug-resistant HIV-1 strains in vitro (PBMC cells) ...