• Do oral contraceptives carry a significant risk of stroke for women with migranes? 

    McClester, Mallory; Mounsey, Anne L.; Mackler, Leslie (Family Physicians Inquiries Network, 2013-11)
    Evidence-based answer: Estrogen-containing oral contraceptives may raise the risk of ischemic stroke in women with migraine, particularly migraine with aura (strength of recommendation [SOR]: C, small case-control studies ...
  • Elevated troponin but no CVD: what's the prognosis? 

    Mantzouris, Tammy; Gauer, Robert; Mackler, Leslie (Family Physicians Inquiries Network, 2013-10)
    Patients with elevated troponin levels and chronic renal disease, pulmonary hypertension, pulmonary embolism, chronic obstructive pulmonary disease, sepsis, or acute ischemic stroke have a 2- to 5-fold increased risk of ...
  • When you suspect ACS, which serologic marker is best? 

    Mitchell, Jonathan; Mackler, Leslie (Journal of Family Practice, 2014-02)
    Measurement of troponin levels provides the most sensitive and accurate serologic information in evaluating a patient with acute coronary syndrome (ACS); troponin elevations are more sensitive than elevations of creatine ...