Browsing by Thesis Advisor "Ray, Bimal K."
Now showing items 1-4 of 4
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Mechanism of induction of vascular endothelial growth factor (vegf) in osteoarthritis
(University of Missouri--Columbia, 2006)Vascular endothelial growth factor (VEGF) is an endothelial cell mitogen and an angiogenic factor. Angiogenesis regulated by VEGF is a critical event in the pathogenesis of Osteoarthritis (OA). Over-expression of VEGF in ... -
Mechanism of matrix metalloproteinase-14 (mmp-14) regulation during atherosclerosis
(University of Missouri--Columbia, 2006)Atherosclerosis is characterized by the narrowing of the arterial lumen due to formation of the plaque within the intimal layer of the arterial wall resulting in the impaired flow of blood to the target organs. Most severe ... -
The role of mTOR in SAF-1-mediated VEGF expression and breast cancer progression
(University of Missouri--Columbia, 2015)Breast cancer is a heterogeneous disease with a huge impact on the community evident from its high indices of morbidity and mortality worldwide. In recent years, research has been extensively directed toward unravelling ... -
Transcriptional regulation of ADAM-12 expression under normal and osteoarthritic conditions
(University of Missouri--Columbia, 2009)ADAM 12 overexpression is linked to the pathology of diseases including osteoarthritis, cancer, cardiac hypertrophy, Alzheimers and multiple sclerosis. Degradation of fibrous cap and neo chondrogenesis are key events of ...