Browsing by Thesis Department "Veterinary medicine and surgery (MU)"
Now showing items 1-20 of 24
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11[beta]-HSD[subscript 2] activity in an equine distal limb and thoracic wound model
(University of Missouri--Columbia, 2009)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Healing of wounds located on the distal limbs of horses is often complicated by exuberant granulation tissue (EGT) causing a delay in wound ... -
Acute phase proteins in naturally occurring respiratory disease of feedlot cattle : a novel approach to diagnosis
(University of Missouri--Columbia, 2014)Bovine respiratory disease (BRD) is the most costly disease of feedlot cattle in the United States. Costs associated with BRD have been estimated from $13.90 to $15.57 per head with annual losses to the cattle industry ... -
Analysis of platlet function in the setting of controlled trauma in dogs using a whole blood electrical impedance platelet aggregometer
(University of Missouri--Columbia, 2017)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Post-traumatic hemorrhage remains one of the leading causes of human deaths, accounting for 30 to 56 percent of pre-hospital post-traumatic deaths. ... -
Angular limb deformities affecting the canine radius and ulna : classification using the center of rotation of angulation method
(University of Missouri--Columbia, 2015)We hypothesized that 1) antebrachial ALDs would be more complex with respect to multiplicity in chondrodystrophic dogs, and 2) more complex ALDs would exhibit a higher incidence of concurrent joint radiographic disease. ... -
Canine T-regulatory cells in aging and cancer : quantifying a unique T cell subset
(University of Missouri--Columbia, 2010)T regulatory lymphocytes (Tregs), identified by the markers CD4, CD25, and FoxP3, are an essential part of the immune system and promote tolerance with the purpose of minimizing auto-immune disease. However, if Tregs are ... -
Detection of Leptospira interrogans in fixed equine eyes affected with end-stage equine recurrent uveitis
(University of Missouri--Columbia, 2007)Equine recurrent uveitis (ERU) is the most frequent cause of blindness in horses worldwide. Leptospira has been implicated as an etiologic agent in some cases of ERU. The objective of this study was to determine the presence ... -
Determination of allergen sensitization and comparison of subcutaneous and mucosal (intranasal) allergen-specific immunotherapy in an experimental model of feline asthma
(University of Missouri--Columbia, 2009)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Rush immunotherapy (RIT) is effective in experimental feline allergic asthma. Further studies evaluating reliable allergen identification and improved ... -
Development of an in-vitro model of equine corneal wound healing : pharmacologic and gene therapy modalities in the reduction of corneal fibrosis
(University of Missouri--Columbia, 2010)Objective: To establish an in vitro model for the investigation of equine corneal wound healing. To accomplish this goal, a protocol to isolate and culture equine corneal keratocytes, fibroblasts and myofibroblasts was ... -
The effects of an antiseritonergic drug and antihistamine in an experimental model of feline asthma
(University of Missouri--Columbia, 2007)Use of cyproheptadine, a serotonin antagonist, and cetirizine a selective histamine (H1) antagonist, in feline asthma has not been previously described. We tested the hypotheses 1) 5 mg of oral cetirizine would be adequately ... -
The effects of temperature and admixture handling on lipid emulsion stability in centrally administered veterinary parenteral nutrition (PN) admixtures
(University of Missouri--Columbia, 2008)This research centered on veterinary parenteral nutrition (PN) admixtures which are mixtures of amino acids, dextrose, and lipid emulsions designed for the intravenous provision of nutrition to small animal patients. ... -
Evaluation of autoimmune disease as a risk factor for lymphoma
(University of Missouri--Columbia, 2013)The immune system has an intricate relationship with cancer. It is responsible for the prevention, management, and resolution of cancer. In people and dogs autoimmune diseases have been linked to hematopoietic neoplasia. ... -
Evaluation of novel diagnostic and therapeutic modalities for treatment of canine pulmonary hypertension
(University of Missouri--Columbia, 2008)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Pimobendan, a phosphodiesterase III inhibitor and calcium channel sensitizing agent, was hypothesized to decrease the severity of pulmonary hypertension ... -
Evaluation of survivin, an inhibitor of apoptosis, in canine urinary bladder tissues
(University of Missouri--Columbia, 2008)Introduction: Survivin, an inhibitor of apoptosis, is overexpressed in human urinary bladder transitional cell carcinoma (TCC). The objectives of this study were to evaluate expression of survivin in canine TCC, cystitis, ... -
Feeding studies of dietary diacylglycerol oil in normal and lipoprotein lipase-deficient cats
(University of Missouri--Columbia, 2008)Diacylglycerol (DAG) oil has been investigated in humans and animals as a potential therapy for hypertriglyceridemia and related disorders. DAG oil was evaluated in healthy cats and in a feline model of hypertriglyceridemia ... -
Fever and pyrexia with verification of thermisters in dogs
(University of Missouri--Columbia, 2008)An elevated body temperature (pyrexia) often accompanies disease. Body temperature measurement is one of the vital parameters in medicine. This thesis contains a literature review of the pathophysiology of temperature ... -
In vitro and ex vivo therapeutic strategies for equine corneal fibrosis
(University of Missouri--Columbia, 2017)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Purpose: The aims were to (1) To explore the impact of equine corneal fibroblast (ECF) to myofibroblast (ECM) differentiation by altering the expression ... -
In vitro three dimensional biomechanical comparison of two internal fixation methods in equine adult radii
(University of Missouri--Columbia, 2007)Radius fracture configurations conducive to internal fixation most often contain a spiral or oblique fracture of the distal diaphysis. The location and fracture configurations are biomechanically challenging because of the ... -
Ketamine immunomodulation during endotoxemia
(University of Missouri--Columbia, 2007)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Previous studies have shown that ketamine attenuates endotoxin (LPS)-induced production of tumor necrosis factor (TNF)-[alpha] in murine models. Because ... -
Local photodynamic therapy for equine squamous cell carcinoma in a murine model
(University of Missouri--Columbia, 2007)The objectives of the present studies were to evaluate the use of local photodynamic therapy (PDT) on tumor growth inhibition in a murine model of squamous cell carcinoma (SCC). SCC was induced in nude mice by injection ... -
Longitudinal evaluation of effects of adipose-derived mesenchymal stem cells in a model of feline allergic asthma
(University of Missouri--Columbia, 2014)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Asthma is characterized by airway inflammation, airway hyperresponsiveness (AHR), and structural changes in the lungs. Mesenchymal stem cells (MSCs) ...