Browsing by Thesis Advisor "Xu, Dong, 1965-"
Now showing items 1-20 of 23
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Analyzing high-throughput genomics data for cancer studies
(University of Missouri--Columbia, 2015)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] NGS data output has increased at a rate that outpaces Moore's law, more than doubling each year since it was invented. Studying such high-throughput ... -
Applications of deep neural networks to protein structure prediction
(University of Missouri--Columbia, 2018)Protein secondary structure, backbone torsion angle and other secondary structure features can provide useful information for protein 3D structure prediction and protein functions. Deep learning offers a new opportunity ... -
Bioinformatics analysis and prediction of protein phosphorylation and other posttranslational modifications
(University of Missouri--Columbia, 2011)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Protein posttranslational modifications (PTM), such as phosphorylation, play essential roles in many aspects of cell life. With the rapid accumulation ... -
Bioinformatics methods for protein identification using peptide mass fingerprinting data
(University of Missouri--Columbia, 2009)Protein identification using mass spectrometry is an important yet partially solved problem in the study of proteomics during the post-genomic era. The major techniques used in mass spectrometry are Peptide Mass Fingerprinting ... -
Complexity reduction and visualization tool for RDF knowledge network application in precision medicine
(University of Missouri--Columbia, 2015)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Precision medicine is one of the most rapidly emerging areas of research and development, crucial for improving patient care, but there is a lack of ... -
Computational analysis of tongue image for health diagnosis
(University of Missouri--Columbia, 2017)Tongue, the primary taste organ in the mouth, can reflect the whole body's health conditions based on the Traditional Chinese Medical (TCM) theories. Watching the tongue is one of the most common, essential and reliable ... -
Computational methods for bacterial characterization and bacteria-host/environment interaction analyses
(University of Missouri--Columbia, 2012)With the rapid development of next-generation sequencing technologies, bacterial identification becomes a very important and essential step in processing genomic data, especially for metagenomic data. Many computational ... -
Data analysis and prediction of protein posttranslational modification
(University of Missouri--Columbia, 2014)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Protein posttranslational modification (PTM) occurs broadly after or during protein biosynthesis, to assist folding or activate function during the ... -
Development of a plant protein phosphorylation database and a web-based protein phosphorylation prediction tool
(University of Missouri--Columbia, 2012)In this project, two efficient and intuitive user-interfaces were designed and developed to be highly accessible and versatile for bioinformatics researchers. Two web based user interfaces were designed for two bioinformatics ... -
Development of Soybean Knowledge Base (SoyKB), a multi-omics data integration web resource for bridging molecular breeding and translational genomics in Glycine Max
(University of Missouri--Columbia, 2013)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Many genome-scale data are available in soybean (Glycine Max) including genomics, transcriptomics, proteomics and metabolomics datasets, together with ... -
Development of tools for SoyKB: SNPViz, differential expression and protein bioviewer
(University of Missouri--Columbia, 2014)Soybean Knowledge Base (SoyKB) is a comprehensive website, which contains lots of web sources for soybean. By integrating multi omics data and solving data storage problem, SoyKB is able to build connection between multiple ... -
Development of web services in academic environment
(University of Missouri--Columbia, 2019)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI--COLUMBIA AT REQUEST OF AUTHOR.] The rapid growth in the use of the World Wide Web (WWW) has been noted by many researchers and practitioners. Web services have become a ... -
Develpment of soybean knowledge base for systems biology studies
(University of Missouri--Columbia, 2014)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Soybean (Glycine max), as an important crop worldwide primarily for protein and oil, has raised great interest in both basic and applied researches. ... -
Genome scale meta analysis of microarrays for biological inferences
(University of Missouri--Columbia, 2009)In this present era of high-throughput technologies, meta-analysis is being widely used to integrate multiple similar high throughput studies. Here we propose a novel framework for applying meta-analysis techniques on ... -
Genome-wide microbial phylogeny reconstruction with polytomy identification
(University of Missouri--Columbia, 2010)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Evolutionary comparative genomics is one of the most studied areas in the computational biology. With ever increasing speed of newly sequenced microbial ... -
Large-scale soybean genome-wide variation workflow and association analysis using deep learning
(University of Missouri--Columbia, 2019)[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] With the advances in next-generation sequencing technology and significant reduction in sequencing costs, it is now possible to sequence large collections ... -
Methods for protein structure prediction
(University of Missouri--Columbia, 2014) -
A novel framework for protein structure prediction
(University of Missouri--Columbia, 2007)Proteins are one of the most important molecules in the life processes. The structure of a protein is essential in understanding the function of a protein at the molecular level. Due to rapid progress in sequencing ... -
Phosphoprotein analysis of soybean root hairs in response to Bradyrhizobium japonicum inoculation
(University of Missouri--Columbia, 2012)The nitrogen fixing symbiosis in soybean (Glycine max) is initiated by colonization of root hairs by the symbiotic bacterium Bradyrhizobium japonicum. Specificity in this symbiosis is determined very early during the initial ... -
PRIMEGENSv2 : a service based platform using object oriented model view controller design pattern
(University of Missouri--Columbia, 2009)There are a number of tools and software packages dealing with the problem of efficient primer and probe design. In an era of fast paced research it is rather difficult for any researcher to change their favorite tool. So ...