• Model-based simulations of the piercing process in piezo-ICSI 

    Gan, Yong, 1976- (University of Missouri--Columbia, 2008)
    To develop a piezo intracytoplasmic sperm injection (piezo-ICSI) procedure without using mercury, the real physics behind the zona piercing must be understood. An effort has been made to formulate a three-dimensional model ...
  • Proteasomal Interference Prevents Zona Pellucida Penetration and Fertilization in Mammals 

    Sutovsky, Peter; Manandhar, Gaurishankar; McCauley, Tod C.; Caamaño, Jose Nestor; Sutovsky, Miriam; Thompson, Winston E.; Day, B.N. (Society for the Study of Reproduction, Inc., 2004-07)
    The ubiquitin-proteasome pathway has been implicated in the penetration of ascidian vitelline envelope by the fertilizing spermatozoon (Sawada et al., Proc Natl Acad Sci U S A 2002; 99:1223-1228). The present study provides ...
  • Ubiquitin C-terminal hydrolase-activity is involved in sperm acrosomal function and anti-polyspermy defense during porcine fertilization 

    Yi, Young-Joo; Manandhar, Gaurishankar; Sutovsky, Miriam; Li, Rongfeng; Jonáková, Vra; Oko, Richard; Park, Chang-Sik; Prather, Randall S.; Sutovsky, Peter (Society for the Study of Reproduction, 2007-11)
    The 26S proteasome, which is a multi-subunit protease with specificity for substrate proteins that are postranslationally modified by ubiquitination, has been implicated in acrosomal function and sperm-zona pellucida (ZP) ...