Search
Now showing items 1-4 of 4
Differential effects of increasing physical activity and reducing energy intake on cardiometabolic and energetic parameters in obesity-prone juvenile rats
(University of Missouri--Columbia, 2015)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Although the rise in adolescent obesity plateaued from 2003 to 2012, health implications associated with excess adiposity in the adolescent years ...
Estrogen signaling and UCP1 : exploring mechanisms to improve metabolic health
(University of Missouri--Columbia, 2018)
Metabolic disease risk rapidly escalates following menopause. The mechanism is not fully known, but likely involves reduced signaling through Estrogen Receptor a (ERa) which is highly expressed in brown (BAT) and white AT ...
The role of estrogen receptor beta DNA binding domain in mediating adipose tissue and systemic metabolic effects of exercise in ovariectomized mice
(University of Missouri--Columbia, 2020)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Estradiol protects women from various cardiovascular and metabolic diseases, a protection which is lost with menopause when estradiol levels drop. ...
Changes in nucleus accumbens gene expression accompany sex specific suppression of voluntary physical activity in aromatase knockout mice
(University of Missouri--Columbia, 2019)
Aromatase is the rate-limiting enzyme in the conversion of testosterone to estrogen and is highly conserved across species. Post-menopause, the aromatase enzyme (locally expressed in adipose tissue, bone, breast tissue, ...