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Enantioselective hydrolysis of 1-arylpropargylic esters by enzymatic kinetic resolution and dynamic kinetic resolution of 1-arylallylic esters
Chiral 1-arylprop-2-en-1-ols and 1-arylprop-2-yn-1-ols are useful building blocks for modern pharmaceuticals. Previous work has found that enzyme catalysis is a potential new enantioselective synthetic route to the former. ...