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Gold nanoparticle-biomolecule conjugates : synthesis, properties, cellular interactions and cytotoxicity studies
(University of Missouri--Columbia, 2008)
This research focuses on conjugation of two major biomolecules i.e., Bombesin and Annexin V, to AuNps and studying their target specificity. The target specificity of AuNps coated with Bombesin, a GRP receptor specific ...
Synthesis and characterization of novel phosphinimine ligand systems for potential applications in radiopharmaceuticals
(University of Missouri--Columbia, 2007)
Multidentate phosphinimine ligands, C₂₅H₄₉N₂P₂Si₂,(2) C₃₄H₃₈N₂P₂Si₂(3), and C₅₀H₆₆N₃P₃Si₃(4), were synthesized in near quantitative yields by Staudinger reaction using appropriate phosphines. Coordination chemistry of 2 ...
Gold nanoparticles for biomedical applications : synthesis, characterization, in vitro and in vivo
(University of Missouri--Columbia, 2006)
Biocompatible gold nanoparticles have gained considerable attention in recent years for potential applications in nanomedicine due to their interesting size dependent chemical, electronic and optical properties. In particular, ...
Palladium nanoparticles encapsulated with resveratrol-derived phenols and polyphenols for targeted prostate cancer therapy
(University of Missouri--Columbia, 2019)
The main goal of this dissertation was to explore the development of a new generation of green nanoformulations through the production of biocompatible palladium nanoparticles using resveratrol to treat, image and evaluate ...
An in-vitro study of the effects of microwave-induced hyperthermia on the cytotoxicity and cellular uptake of resveratrol gold nanoparticles in prostate and pancreatic cancer cells
(University of Missouri--Columbia, 2016)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Cancer has become the second leading cause of death in the United States over the past decade. While conventional methods of treatment such as ...
Quantification of absorbed doses from radioactive gold nanoparticles and chromium 51 seed implants
(University of Missouri--Columbia, 2012)
In the ever ending search to seek better options of treatments in radiation therapy, few novel approaches are presented in this thesis. The work presented is in 2 folds. Potentially both can be applied in radiation dose ...
Synthesis and evaluation of radioactive gold nanoparticles for cancer treatment and imaging
(University of Missouri--Columbia, 2015)
This research study explores an appropriate method for production of radioactive gold nanoparticles that may be more appropriate for treating cancer. The first protocol includes using a nontoxic and antitumor phytochemical ...