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Molecular mechanisms of tumor invasion in three-dimensional collagen matrices
(University of Missouri--Columbia, 2007)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Cancer remains a significant cause of morbidity and mortality worldwide, and invasion and metastasis substantially contribute to poor prognosis and ...
Molecular control of endothelial lumen formation by Rho GTPases in three dimensional collagen matrices
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Rho GTPases regulate a diverse spectrum of cellular functions involved in vascular morphogenesis. Here, we show that Cdc42 and Rac1 play a key role ...