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Functional studies of hCTR1, a high affinity human copper and cisplatin transporter
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Copper is an essential nutrient. The uptake of copper is mediated by the human copper transporter 1 (hCTR1) protein at the plasma membrane. Elevated ...
Inflammation and hypoxia : novel regulators of mammalian copper homeostasis in macrophages
(University of Missouri--Columbia, 2008)
Copper is an essential cofactor of enzymes involved in a variety of important metabolic processes including ATP production, iron transport, and antioxidant defense. The maintenance of copper homeostasis requires a balance ...
Molecular and cell biological studies of mammalian zinc transporters
(University of Missouri--Columbia, 2007)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Zinc is an essential trace element in all organisms. The importance of the hZIP4 human zinc transporter is highlighted by its causative role in a ...
Regulation of copper homeostasis and inflammation in microglial cells
(University of Missouri--Columbia, 2009)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Disturbed copper homeostasis has been shown to implicate in the pathogenesis of AD, as evidenced by high accumulation of copper in the senile plaques. ...