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Modification of porcine rhodopsin by CRISPR/Cas9 : towards a model for Retinitis Pigmentosa
(University of Missouri--Columbia, 2016)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Retinitis Pigmentosa (RP) is a disease characterized by progressive vision loss, which affects approximately 1 in 4,000 people in the United States. ...
Genetic linkage of multiple modifications in the pig
(University of Missouri--Columbia, 2015)
Genetic engineering facilitates heritable modification of target genomes. Modifications can be site-specific or random. Though inefficient, homologous recombination allows for precise genome modification. Random integration ...