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Regulation of calcium signaling by p130PH in astrocytes
(University of Missouri--Columbia, 2009)
Ca2+ signaling is a characteristic form of astrocyte excitability, but its role in ischemia is not clearly understood. Our previous study (Ding et al., 2009) demonstrated that astrocytes exhibit enhanced Ca2+ signaling ...
The impact of neuronal Nampt on motor function of mice
(University of Missouri--Columbia, 2016)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Nicotinamide phosphoribosyltransferase (Nampt), also named visfatin and pre-B cell colony-enhancing factor (PBEF), is the rate-limiting enzyme converting ...
The role of metabotropic glutamate receptor 5 in cerebral ischemia
(University of Missouri--Columbia, 2014)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Group I metabotropic glutamate receptor 5 (mGluR5), belongs to G-protein coupled receptors family and plays important roles in CNS disorders including ...
Deletion of IP₃ receptor2 in astrocytes enhances the hippocampal neurogenesis in adult mice
(University of Missouri--Columbia, 2014)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Neurogenesis (birth of neurons) is a process by which neurons are generated from neural progenitor cells. It mainly occurs in two regions of brain, one ...
The role of astrocytic calcium signaling in brain damage after photothrombosis
(University of Missouri--Columbia, 2011)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Ischemic stroke is the third leading cause of death in industrialized countries. Our previous study found elevated [Ca[superscript 2+]]i signals in ...
The role of Pre-B-cell colony-enhancing factor in neuronal death after ischemia and motor dysfunction
(University of Missouri--Columbia, 2016)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Pre-B-cell colony-enhancing factor (PBEF) is the rate-limiting enzyme in the salvage pathway of mammalian nicotinamide adenine dinucleotide (NAD+) ...