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The role of resistance exercise training & IGF-1 signaling in the amelioration of mild cognitive impairment in female Wistar rats
(University of Missouri--Columbia, 2021)
Mild cognitive impairment increases risk for dementia. One therapeutic intervention that is reported to ameliorate cognition in patients with mild cognitive impairment is resistance exercise. However, the underlying ...
Evaluating the molecular drivers of physical inactivity and muscle atrophy as initiating factors in cognitive impairment
(University of Missouri--Columbia, 2023)
decreased Glutamate AMPA Receptor 1 (GluA1) protein levels, and neurogenesis. Our genetic model for high physical activity on the other hand had enhanced performance in cognitive behavioral testing, increased hippocampal volumes, and increased markers...