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Pharmacological targeting of plasminogen activator inhibitor-1 decreases vascular smooth muscle cell stiffness and cytoskeletal F-actin stress fiber density
(University of Missouri--Columbia, 2021)
Vascular stiffness plays a key role in cardiovascular diseases, and recent studies suggest that intrinsic stiffness of vascular smooth muscle cells (SMCs) accounts for as much as one-half of overall arterial stiffness. ...