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Modeling HIV-1 Infection in the Brain: The Effect of the Blood-Brain Barrier
(2019)
Despite the advancement of antiretroviral therapy (ART), the development of HIV associated neurocognitive disorders (HAND) remains a major concern among HIV infected patients. As many ART drugs may fail to penetrate the ...
Modeling the Effects of Drugs of Abuse on HIV Infections with Two Viral Species
(University of Missouri--Kansas City, 2017)
Injection drug use is one of the greatest risk factors associated with contracting human
immunodeficiency virus (HIV), and drug abusers infected with HIV suffer from
a higher viral load and rapid pathogenesis. Replication ...
Modeling HIV-1 Infection and Immune Responses Under Drugs of Abuse
(University of Missouri -- Kansas City, 2018)
The frequent use of drugs of abuse among HIV infected individuals is a major
concern. Drugs of abuse, such as opiates, have been widely associated with enhanc
ing HIV replication, accelerating disease progression, and ...